We aim to translate current understanding to prevent disease onset, prevent complications and improve long-term outcome.
Precision medicine has the potential to have an enormous impact on healthcare, however for this potential to be fully realised we need to be able to accurately predict the outcome of patients in different clinical scenarios.
The major challenge now is to integrate genetic and clinical datasets to maximise predictive performance which is a challenge that can only be met by the interdisciplinary efforts of geneticists, clinicians, computer scientists and epidemiologists.
Example studies include:
- Preventing disease – if psoriasis patients at highest risk of progression to psoriatic arthritis can be identified, prevention trials become a realistic possibility.
- Preventing morbidity– understanding the basis for the increased prevalence of comorbidities in patients with inflammatory arthritis will help us develop preventative strategies.