Research themes
Our research is divided into two programmes that work together with the aim of translating genetic discoveries into treatments for musculoskeletal conditions.
Translational genetics
Preventing disease
We translate current understanding to prevent disease onset, prevent complications and improve long-term outcome.
Predicting treatment response
We aim to improve measures of treatment outcome, understand the impact of confounding, and discover novel biomarkers.
Personalising treatment
We aim to investigate failure of current treatment and attempt to identify new treatments.
Functional genetics
Functional mechanisms
Our research focuses on the identification of causal variants and genes within regions associated with complex traits, using a combination of genetic analysis, bioinformatic tools and functional experiments.
Immunophenotyping
We aim to characterise how immune cells change as a result of carrying DNA variants that increase the risk of disease.
Bioinformatics
We aim to provide bioinformatics solutions to analyse and interpret the increasing wealth of data, primarily sequencing data, in the post-genomic era.